Maintaining cell viability is crucial for obtaining authentic and reliable data in long-term imaging. Controlling and maintaining temperature, pH, and humidity, as well as low light pressure and workbench stability, are prerequisites for successful experiments. Transforming the perspective from individual microscope components to a complete live cell imaging solution, the Leica microscopy system integrates the microscope, LAS X imaging software, camera, and specialized third-party components into the Leica DMi8 live cell imaging system.

Advanced Fluorescence Imaging System

To understand complex cellular processes, observing and interacting with your sample requires multiple techniques. Multidimensional imaging with up to 6 parameters (x, y, z, t, λ, n) is required to provide a comprehensive dataset for studying cell activity on a larger scale and at greater depth. Accurate visualization and comprehensive analysis of collected data are crucial in obtaining the correct answers to research questions. The Leica DMi8 solution for advanced imaging combines precision tools for obtaining high-resolution accurate data with powerful and easy-to-use analysis capabilities.

Microscopic operating system and ICSI configuration

In many delayed or multidimensional experiments, cell processing is the starting point for subsequent analysis. Microinjection of DNA, RNA, or probes into adherent cells allows you to better understand pathways and intracellular structures. Microinjection of DNA, stem cells, or sperm into oocytes or blastocysts to create transgenic or cloned organs, or fertilization of oocytes for assisted reproductive technologies (ART) such as in vitro fertilization (IVF). Several configurations of Leica DMi8 meet your needs and budget, and you are sure to find the perfect microscopy solution.

Quantitative imaging system

Understanding the interactions between organelles, signaling pathways, and proteins is crucial for decoding the fundamental processes of life. Ratio imaging and FRET measurement, like other quantitative methods, help decipher molecular mechanisms. The aggregated data will enhance existing scientific insights and become the foundation for discovering more effective drugs and medical methods.