Non contact ultrasonic crusher, also known as cup crusher, is used for aseptic crushing. It can break chromosomes and cells through a centrifuge tube. Specially tailored for the pre-treatment of second-generation sequencing DNA samples and chromatin immunoprecipitation experimental samples, compared to traditional probe contact ultrasonic cell crushers, non-contact samples can be crushed in a sealed container without producing infectious flying mist. The ultrasonic probe does not come into contact with the sample to avoid cross contamination. The non-contact ultrasonic crusher can achieve unparalleled quality, efficiency, and safety compared to traditional ultrasonic methods.

Multiple samples can be tested simultaneously with high experimental efficiency; There is no wear or debris, and all products are stored in separate fully enclosed test tubes to avoid cross contamination; Optional cooling water circulation system is available, which facilitates the ultrasonic treatment of samples in a 4 ℃ water bath with uniform energy distribution and complete ultrasonic effect; The ultrasound parameter settings are flexible, the experimental steps are standardized, the experimental reproducibility is good, and the results are highly reliable.

Gradually becoming an indispensable standardized tool for ChIP (chromatin immunoprecipitation) and DNA splicing research platforms. The experimental efficiency is high, the results are reliable, and the repeatability is good. It can handle a minimum of 5ul of samples and is suitable for precious samples.

Performance characteristics

1. Non aerosol aerosol production - enhances biosafety (such as mycobacteria, viruses, etc.)

2. Eliminating the risk of sample cross contamination

Eliminating the traditional phenomenon of probe wear and debris

4. Can handle a variety of samples, with a wide range of sample processing capabilities

5. Suitable for various standard containers

⒍ Can be used to process trace samples, with a minimum of 5ul

The automatic continuous rotation of the centrifuge tube makes the energy distribution of ultrasound more uniform

⒏ Optional high and low temperature constant temperature water bath

Application scope

1. DNA fragmentation

2. RNA Fragmentation

3. Bacterial and cellular fragmentation

ChIP assay (chromatin immunoprecipitation)

5. Sample pre-processing for high-throughput sequencing machines

⒍ Membrane protein extraction

Homogenization and emulsification reaction

Ultrasonic treatment of valuable reagents

advantage

Compared to the longitudinal ultrasound used in the market, due to the fact that the test tube is perpendicular to the end face, ultrasound causes uneven fragmentation of the sample. The larger the test tube, the more pronounced this unevenness becomes. And our company uses transverse ultrasound, which makes it easier to penetrate the test tube.

The rotation system and vibration system of the test tube disk enable low-frequency movement of the sample inside the test tube, resulting in more uniform ultrasound.