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【 Silicon Instrument Technology 】 Agilent/Agilent 1200 Series Liquid Chromatography System
Based on the new ZORBAX chromatography technology and system design, your analysis time can be reduced by about 20 times. The separation degree has in
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Product Description

Based on the new ZORBAX chromatography technology and system design, your analysis time can be reduced by about 20 times. The separation degree has increased by 60%. A more intuitive user interface enables you to easily control and monitor the status of the instrument.


Agilent 1200 series liquid chromatography instrumentEnable you to access higher quality data faster. Modular design ensures reliability and investment protection.Agilent 1200 series liquid chromatographyThe system will undoubtedly meet your current and future application needs. Based on the new ZORBAX chromatography technology and system design, your analysis time has been greatly reduced. The separation degree has increased significantly. A more intuitive user interface enables you to easily control and monitor the status of the instrument. The new options in data analysis provide fast and effective data browsing tools. Agilent diagnostic software supports "intelligent services".

1. Rapid high separation liquid phase system

existAgilent 1200Compared with conventional HPLC, the series of fast and high separation LC systems have significantly increased analysis speed and high resolution without sacrificing resolution, precision, and sensitivity. The Agilent 1200 series fast and high separation liquid phase system is designed to provide faster analysis speed, higher resolution, while maximizing the maintenance of low system pressure. Therefore, it retains the durability and working principle of conventional HPLC instruments and methods. This unique design makes the 1200 RRLC a universal liquid phase analysis flow rate range suitable for column sizes ranging from 1 to 4.6-mm ID, 10 to 300-mm column length, and particle size ranging from 1.5 to 10 µ m.
characteristic:
  • 20 times faster than conventional HPLC and with the same or better data quality (resolution, sensitivity, precision).
  • Compared to HPLC, the high resolution has been improved many times. Having the same or better data quality (resolution, sensitivity, precision).
  • The delay volume is configurable and suitable for various applications.Can support both narrow diameter columns and standard columns - suitable for RRLC and HPLC.
  • Does not affect the compatibility of existing HPLC methods. Standard delay volume configuration (600-800 µ L), column length 300 mm.
  • More suitable for supporting LC/MS on narrow diameter columns. Low latency volume configuration (120 µ L).
  • Regulatory adaptability, meeting stricter regulatory requirements.
  • There are many types of RRHT columns with wide applicability.
  • A simple, rapid, and reliable method for transferring RRHT from HPLC to RRLC can be achieved. RRHT and HPLC columns have the same chemical properties.
  • High throughput configuration, achieved through alternating column regeneration (ACR), the system includes 2 pumps, 2 chromatography columns, and a 2Ps/10Pt valve for alternating column switching.
  • Typical performance:It is many times faster than standard liquid chromatography, with a resolution increase of many times compared to standard liquid chromatography. The retention time precision is generally less than 0.1% RSD, and the peak area precision is generally less than 0.5% RSD. It can quantify impurities at the 0.03% level. The LOD of anthracene is less than 1 pg, which is compatible with conventional liquid chromatography methods.

2. Binary liquid phase system

When you need higher gradient and low flow accuracy and precision, the performance of the Agilent 1200 series binary gradient system is a worthwhile choice. It is an ideal system for many high-throughput and ultra fast applications, suitable for most high-throughput and fast applications.
characteristic:
  • The flow range is from 0.050 to 5 mL/min, suitable for micro diameter columns, 2.1 and 4.6 mm columns.
  • Optimized the system delay volume for rapid chromatography.
  • For improved convenience and flexibility, a programmable solvent selector valve can be chosen, combining two of the four solvents to provide four different binary combinations with greater flexibility.
  • Early Maintenance Feedback (EMF) enables you to monitor instrument usage continuously over the long term.
  • Programming and control can be easily achieved through the Instant Pilot component, Agilent Chemical Workstation, or EZChrom software.
  • Quickly replace maintenance components directly from the front panel.
  • Quickly identify issues through self diagnosis, built-in logs, and pre programmed testing methods.
  • Early Maintenance Feedback (EMF) continuously monitors instrument usage and user preset limits, and provides feedback information once the limits are exceeded.

3. Quaternary liquid phase system


Agilent 1200The series of quaternary pumps are suitable for method development, research, and various applications that require continuous and extensive solvent selection, providing greater flexibility in solvent selection and automation. The Agilent 1200 quaternary system can quickly switch between methods using different solvents and can use binary, ternary, and quaternary gradients, making it a more flexible system on the market. And anyAgilent 1200After combining the series of automatic samplers, the Agilent 1200 series quaternary system is highly suitable for multi method high-throughput workflows.
characteristic:
  • Convenient use of four solvents for equal gradient or gradient analysis, suitable for rapid method development and rapid preparation of mobile phases, as well as flushing HPLC systems.
  • Wide flow range, higher flow rate of 10 mL/min, delay volume of 800-1100 µ L, suitable for micro diameter columns, standard columns, and semi preparative applications.
  • Programming and control can be easily achieved through the Instant Pilot component, Agilent Chemical Workstation, or EZChrom software.
  • Contains a micro vacuum degassing machine with high degassing efficiency, achieving barrier free operation and higher performance without the need for helium gas supply
  • Quickly replace maintenance components directly from the front panel.
  • Quickly identify issues through self diagnosis, built-in logs, and pre programmed testing methods.
  • Upgradeable and expandable within the range of other Agilent 1200 series HPLC components.

4. Unit liquid phase system

Agilent 1200The series unit system is designed for QA/QC applications and other applications that require high-performance economical HPLC systems. The Agilent 1200 series unit system is designed in a modular manner and is an ideal startup system. It can be fully upgraded to meet future needs, expand system performance, or add automation and detector components, thus protecting your Agilent 1200 series unit system. It has excellent durability, reliability, and many built-in efficient functions. The small chassis contains advanced hardware. This system is easy to maintain and fast, and users only need a little training to work. It is a system worth owning and using.
characteristic:
  • Strict design enables it to have long normal operation time and consistent results at low operating and maintenance costs.
  • Open the front panel to handle and maintain components, and quickly replace them without disassembling the instrument.
  • There are printed instructions for installation, performance verification, operation, preventive maintenance, and system suitability testing, and video demonstrations of general maintenance steps are available on the CD-ROM.
  • The flow range is wide, with a flow rate of up to 10 mL/min, suitable for a wide range of HPLC applications, including semi preparative separations.
  • Early Maintenance Feedback (EMF) enables you to monitor instrument usage continuously over the long term.
  • Built in self checking programs, logs, and pre programmed testing methods help to quickly identify issues.
  • QA/QC operations have task oriented online assistance.
  • Full programming functionality, such as intelligent method sequences, including internal termination methods, to help save solvents and extend column life.
  • High sensitivity variable wavelength detector, with the lowest detection limit and the lowest baseline noise, fully programmable wavelength switching throughout the process, optimized selectivity for the eluted analyte, suitable for fast wavelength optimized stop flow wavelength scanning.
  • Unit to quad upgrade toolkit, expanding from 1 solvent to 4 solvents.

5. Purification system

Agilent Technologies' HPLC system, with its high reliability, has been expanded to include purification functions, ranging from low milligrams to grams. The Agilent 1200 series purification platform provides a flexible and precise solution for preparing HPLC. This precise, high-throughput LC system can optimize the amount of sample to be separated, improve purity and recovery, and achieve the desired sample flux and analysis cost.
  • Expert systems suitable for different applications:Optimize high purity and recovery rate to achieve the desired sample flux and analysis cost. The specialized components for purification include Agilent 1200 series preparation pump, Agilent 1200 series dual quantitative tube automatic samplerAgilent 1200Series fraction collectors and Agilent 1200 series trace collection/sampling systems.
  • Higher purity and recovery rate avoid peak diffusion and cross contamination between fractions.
  • The unique delay sensor makes delay volume correction an easy task.
  • The concentration of safety concepts, safety leakage treatment/detection, and forced evaporation extraction gives you the confidence to walk away, allowing you to use the system outside the fuel cupcake.
  • Collecting fractions by time, peak, and/or mass (or manually) allows you to collect only the fractions you need.
  • Recycling collection ensures no omissions.
  • Accurate, consistent, and programmable slit ratio is achieved by actively diverting and collecting fractions by mass.
  • Real time data processing, high-precision fraction triggering control local area network (CAN).
  • Single vendor solution.All equipment, consumables, and technical support come from the same manufacturer

6. HPLC-Chip/MS system

Agilent 1200 series liquid chromatography-The chip/mass spectrometry system is a nanofluidic chromatography/electrospray mass spectrometry platform based on a new microfluidic technology. Based on Agilent's liquid chromatography-chip and liquid chromatography-chip/mass spectrometry interface technologies, Agilent's new liquid chromatography-chip/mass spectrometry system has brought nanofluidic electrospray mass spectrometry to a new level, namely, high sensitivity, high reliability, high durability and ease of operation.

7. Flow liquid phase system

Nanoflow LC is widely used for high-resolution separation and high-sensitivity MS detection. The Agilent 1200 series nanoflow LC combines Agilent's electronic flow control (EFC), as well as active feedback and real-time flow regulation functions, to deliver stable flow to the chromatographic column, independent of system backpressure. EFC is first introduced together with the 1100 series capillary and nanoflow LC pump, which can perform real-time flow control and is the gold standard for reliable and durable nanoflow performance. It is easy to use,Agilent 1200The series of nanoflow LC only requires users to simply input the desired nanoflow set point to obtain accurate flow rate and gradient, thereby ensuring the repeatability of retention time and stable ions required for high sensitivity nanoflow MS performance.

8. Capillary liquid phase system


Agilent 1200The series capillary liquid chromatography system is based on the reliable Agilent 1200 series liquid chromatography system, using unique technology to optimize the capillary liquid chromatography system, with high sensitivity and reproducibility.
characteristic:
  • Has high sensitivity and reproducibility.
  • Excellent performance - retention time stability is not affected by post column pressure.
  • Delay volume reduction.
  • The flow rate ranges from 1 µ L/min to 100 µ L/min, providing the full gradient function required for capillary liquid chromatography. In standard mode, the highest flow rate is 2.5 mL/min, which has a wide range of application flexibility.
  • The combination of high-precision capillary liquid chromatography separation and sensitive MS detection provides a complete solution for trace sample processing and detection of extremely low analyte concentrations.
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